ALEXANDRIA, Va., July 9 -- United States Patent no. 12,351,826, issued on July 8, was assigned to RIGENERAND S.R.L. (Medolla, Italy).
"Method to produce conditionally apoptotic cells" was invented by Filippo Rossignoli (Verona, Italy), Carlotta Spano (Modena, Italy), Giulia Grisendi (Reggio Emilia, Italy), Olivia Candini (Crevalcore, Italy) and Massimo Dominici (Ferrara, Italy).
According to the abstract* released by the U.S. Patent & Trademark Office: "The method to produce conditionally apoptotic cells comprises modifying a cell population with a phenotype attributable to human adipose tissue-derived pericytes (AD-PC) expressing anti-tumor TRAIL introducing a sequence coding a conditional suicide gene (CSG)."
The patent was filed on Ma...