US Patent Issued to Rigel Pharmaceuticals on Oct. 21 for "Solid forms of pralsetinib" (Canadian, American Inventors)

ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,448,366, issued on Oct. 21, was assigned to Rigel Pharmaceuticals Inc. (South San Francisco, Calif.).

"Solid forms of pralsetinib" was invented by Joshua Waetzig (Cambridge, Mass.), Gordon D. Wilkie (Cambridge, Mass.), Lauren MacEachern (Halifax, Canada) and Kimberly Jean Miller (Halifax, Canada).

According to the abstract* released by the U.S. Patent & Trademark Office: "The compound cis)-N-((S)-1-(6-(4-fluoro-1H-pyrazol-1-yl)pyridin-3-yl)ethyl)-1-methoxy-4-(4 methyl-6-(5-methyl-1H-pyrazol-3-ylamino)pyrimidin-2-yl)cyclohexanecarboxamide can be prepared as a free base in various crystalline solid forms, and in various salt forms each having one or more solid forms."

The patent was f...