ALEXANDRIA, Va., June 9 -- United States Patent no. 12,285,460, issued on April 29, was assigned to RHYTHM PHARMACEUTICALS INC. (Boston).

"Pharmaceutical compositions" was invented by Shubh Sharma (Cranbury, N.J.), Leonardus H. T. Van Der Ploeg (Newton, Mass.) and Bart T. Henderson (Belmont, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to an ionic complex comprising a cationic polypeptide and an anionic excipient selected from: a PEG-carboxylic acid; a fatty acid having 10 or more carbon atoms; an anionic phospholipid; and a combination thereof. The invention also relates to a pharmaceutical composition comprising the ionic complex of the invention and a pharmaceutically...