US Patent Issued to RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN on Sept. 9 for "Mutated arylsulfatase a" (German Inventors)

ALEXANDRIA, Va., Sept. 10 -- United States Patent no. 12,410,415, issued on Sept. 9, was assigned to RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN (Bonn, Germany).

"Mutated arylsulfatase a" was invented by Ulrich Matzner (Bonn, Germany) and Volkmar Gieselmann (Alfter, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention pertains to a novel treatment of pathologies caused by an increased synthesis or accumulation of sulfolipids such as sulfatide. The invention provides mutated arylsulfatase A (ARSA or ASA, EC 3.1.6.8) enzymes with increased activity towards sulfatide metabolization. The invention provides nucleic acids encoding the mutant ARSA, the use of the proteins and nucleic acid...