ALEXANDRIA, Va., March 19 -- United States Patent no. 12,252,497, issued on March 18, was assigned to Revolution Medicines Inc. (Redwood City, Calif.).
"Ras inhibitors" was invented by G. Leslie Burnett (Redwood City, Calif.), James Cregg (Belmont, Calif.), Anne V. Edwards (San Mateo, Calif.), Adrian L. Gill (Atherton, Calif.), John E. Knox (Emerald Hills, Calif.), Elena S. Koltun (Foster City, Calif.), Jennifer Pitzen (Fremont, Calif.) and Christopher Semko (Fremont, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention features macrocyclic compounds, and pharmaceutical compositions and protein complexes thereof, capable of inhibiting Ras proteins, and their uses in the treatment of cancers."...