US Patent Issued to REVOLUTION MEDICINES on Feb. 10 for "C40-, C28-, and C-32-linked rapamycin analogs as mTOR inhibitors" (California Inventors)

ALEXANDRIA, Va., Feb. 11 -- United States Patent no. 12,544,448, issued on Feb. 10, was assigned to REVOLUTION MEDICINES INC. (Redwood City, Calif.).

"C40-, C28-, and C-32-linked rapamycin analogs as mTOR inhibitors" was invented by James Bradley Aggen (Redwood City, Calif.), G. Leslie Burnett (Redwood City, Calif.), Jennifer Pitzen (Redwood City, Calif.) and Arun P. Thottumkara (Redwood City, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to mTOR inhibitors. Specifically, the embodiments are directed to compounds and compositions inhibiting mTOR, methods of treating diseases mediated by mTOR, and methods of synthesizing these compounds."

The patent was filed on April 3...