US Patent Issued to RESEARCH TRIANGLE INSTITUTE on Aug. 19 for "Proline-based neuropeptide FF receptor modulators" (North Carolina Inventors)

ALEXANDRIA, Va., Aug. 20 -- United States Patent no. 12,390,446, issued on Aug. 19, was assigned to RESEARCH TRIANGLE INSTITUTE (Research Triangle Park, N.C.).

"Proline-based neuropeptide FF receptor modulators" was invented by Yanan Zhang (Apex, N.C.) and Thuy Nguyen (Morrisville, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Neuropeptide FF receptor modulators based on a proline scaffold are provided which offer NPFF receptor potencies in the nanomolar range and antagonistic selectivity for the NPFF1 receptor. Methods, compounds and compositions for modulating the function of neuropeptide FF receptors are provided for pharmacotherapies capable of influencing conditions or disorders affected by the ne...