ALEXANDRIA, Va., March 26 -- United States Patent no. 12,257,530, issued on March 25, was assigned to Repligen Corp. (Waltham, Mass.).
"Fc binding proteins with cysteine in the c-terminal helical region" was invented by Erik Fiedler (Halle/Saale, Germany) and Ulrich Haupts (Halle/Salle, Germany).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to Fc binding proteins comprising one or more domains with Cysteine in the C-terminal helical region. The invention further relates to affinity matrices comprising the Fc binding proteins of the invention. The invention also relates to a use of these Fc binding proteins or affinity matrices for affinity purification of immunoglobulins and to ...