US Patent Issued to Rensselaer Polytechnic Institute on May 13 for "Systems and methods for inhibiting Gamma-secretase production of amyloid-Beta peptides" (New York Inventor)

ALEXANDRIA, Va., June 12 -- United States Patent no. 12,297,244, issued on May 13, was assigned to Rensselaer Polytechnic Institute (Troy, N.Y.).

"Systems and methods for inhibiting Gamma-secretase production of amyloid-Beta peptides" was invented by Chunyu Wang (Latham, N.Y.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Inhibitors are provided for targeting Gamma-secretase to reduce amyloid load as a viable strategy in Alzheimer's disease treatment and drug discovery. Gamma-secretase has been shown to cleave amyloid precursor protein, causing an increase in extracellular concentration of amyloid-Beta peptides. This extracellular concentration increase can lead to build-up amyloid plaques in patients and as...