US Patent Issued to Rensselaer Polytechnic Institute on Aug. 19 for "Systems and methods for increased production of recombinant biopolymers via genome engineering and downregulation of basal expression" (New York Inventors)

ALEXANDRIA, Va., Aug. 20 -- United States Patent no. 12,391,912, issued on Aug. 19, was assigned to Rensselaer Polytechnic Institute (Troy, N.Y.).

"Systems and methods for increased production of recombinant biopolymers via genome engineering and downregulation of basal expression" was invented by Alexander Joseph Connor (Slingerlands, N.Y.), Mattheos Koffas (Niskayuna, N.Y.), Runye Zha (Troy, N.Y.) and Derek Nelson (Troy, N.Y.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Recombinant E. coli strains and synthetic protein sequence designs are leveraged for production of disordered polypeptides such as spidroins and elastin-like peptides (ELPs). These disordered polypeptides, the high-titer production of whi...