ALEXANDRIA, Va., March 19 -- United States Patent no. 12,251,388, issued on March 18, was assigned to REMEDY PHARMACEUTICALS INC. (New York).
"Methods of treating ischemic stroke at risk for cerebral or cerebellar edema" was invented by Sven Martin Jacobson (New York) and Thomas W. Macallister (Montross, Va.).
According to the abstract* released by the U.S. Patent & Trademark Office: "This disclosure relates to the treatment of ischemic stroke at risk of brain swelling using SUR1-TRPM4 channel inhibitors. In some embodiments, the methods include treating patients suffering from a large hemispheric infarction. In certain embodiments, patients have a baseline NIHSS of less than equal to20. In other embodiments, patients have lesion volume o...