ALEXANDRIA, Va., Nov. 11 -- United States Patent no. 12,465,486, issued on Nov. 11, was assigned to Regents of the University of Minnesota (Minneapolis).

"Engineered valve and method of making" was invented by Zeeshan Syedain (Minneapolis) and Robert Tranquillo (Arden Hills, Minn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This disclosure provides a tissue-engineered transcatheter vein valve and methods of making such a tissue-engineered transcatheter vein valve. Methods of making the valve include casting or molding a polymer into a tubular structure having a first end and a second end, where the first end of the tubular structure is cast or molded around a tubular support structure and where the second...