US Patent Issued to Regents of the University of Minnesota on June 3 for "NK engager molecules and methods of use thereof" (Minnesota Inventors)

ALEXANDRIA, Va., June 4 -- United States Patent no. 12,319,737, issued on June 3, was assigned to Regents of the University of Minnesota (Minneapolis).

"NK engager molecules and methods of use thereof" was invented by Jeffrey S. Miller (Minneapolis), Martin Felices (Minneapolis), Daniel A. Vallera (Minneapolis) and Todd R. Lenvik (Minneapolis).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are compositions for activating NK cells to stimulate an immune response for treating cancer and other disorders. In one embodiment, the invention provides a compound comprising an NK engaging domain that binds to CD 16; an NK activating domain operably linked to the NK engaging domain; and a targeting domain that ...