US Patent Issued to Regeneron Pharmaceuticals on Oct. 7 for "Quantitation and modeling of quality attributes of therapeutic monoclonal antibodies" (New York Inventors)

ALEXANDRIA, Va., Oct. 8 -- United States Patent no. 12,437,836, issued on Oct. 7, was assigned to Regeneron Pharmaceuticals Inc. (Tarrytown, N.Y.).

"Quantitation and modeling of quality attributes of therapeutic monoclonal antibodies" was invented by Xiaobin Xu (White Plains, N.Y.) and Yu Huang (Ossining, N.Y.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods of predicting an in vivo serum concentration of an antibody with a post-translational modification of interest after administration of the antibody are provided, as are methods for predicting a subject's exposure to post-translational variants of the antibody. The methods include predicting a percentage of the antibody with the post-translational m...