US Patent Issued to Regeneron Pharmaceuticals on Oct. 21 for "Target residual moisture content for lyophilized drug product" (Connecticut, New Jersey, New York Inventors)

ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,449,198, issued on Oct. 21, was assigned to Regeneron Pharmaceuticals Inc. (Tarrytown, N.Y.).

"Target residual moisture content for lyophilized drug product" was invented by Xiaolin Tang (Old Tappan, N.J.), Mary Kleppe (Milford, Conn.), Ravi Chari (Norwich, Conn.) and Franco Tzul (Cortlandt Manor, N.Y.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Lyophilization methods for preparing protein formulations for long-term storage at room temperature or improved stability at refrigeration storage are provided. Specifically, the present application provides lyophilization methods to obtain a target percentage of residual moisture of a lyophilized product, su...