US Patent Issued to REGENERON PHARMACEUTICALS on Nov. 25 for "Method for generating high affinity antibodies" (New York, New Jersey Inventors)

ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,480,947, issued on Nov. 25, was assigned to REGENERON PHARMACEUTICALS INC. (Tarrytown, N.Y.).

"Method for generating high affinity antibodies" was invented by Gang Chen (Yorktown Heights, N.Y.), Robert Babb (River Edge, N.J.) and James P. Fandl (LaGrangeville, N.Y.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to a method for identifying cells that express antigen-specific antibodies with a high binding affinity for a monomeric antigen. Using fluorescence activated cell sorting, cells expressing high affinity antigen-specific antibodies are selected from a population of immune cells isolated from a mammal that has been im...