US Patent Issued to Regeneron Pharmaceuticals on May 27 for "Humanized IL-4 and IL-4RAlpha animals" (New York, California Inventors)

ALEXANDRIA, Va., June 17 -- United States Patent no. 12,310,340, issued on May 27, was assigned to Regeneron Pharmaceuticals Inc. (Tarrytown, N.Y.).

"Humanized IL-4 and IL-4RAlpha animals" was invented by Li-Hsien Wang (Somers, N.Y.), Yingzi Xue (Ardsley, N.Y.), Andrew J. Murphy (Croton-on-Hudson, N.Y.) and Sean Stevens (Del Mar, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Non-human animals comprising a human or humanized IL-4 and/or IL-4RAlpha nucleic acid sequence are provided. Non-human animals that comprise a replacement of the endogenous IL-4 gene and/or IL-4RAlpha gene with a human IL-4 gene and/or IL-4RAlpha gene in whole or in part, and methods for making and using the non-human animals, ar...