US Patent Issued to Regeneron Pharmaceuticals on March 4 for "N-terminal scFv multispecific binding molecules" (New York Inventors)

ALEXANDRIA, Va., March 5 -- United States Patent no. 12,240,908, issued on March 4, was assigned to Regeneron Pharmaceuticals Inc. (Tarrytown, N.Y.).

"N-terminal scFv multispecific binding molecules" was invented by Yang Shen (Scarsdale, N.Y.), Ann-Hwee Lee (Ardsley, N.Y.), Yan Yang (Mamaroneck, N.Y.) and Chia-Yang Lin (Scarsdale, N.Y.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Multispecific binding molecules (MBMs) comprising an N-terminal scFv, a first Fab and a second Fab, MBM conjugates comprising the MBMs and cytotoxic or cytostatic agents, pharmaceutical compositions containing the MBMs and MBM conjugates, methods of using the MBMs, MBM conjugates and pharmaceutical compositions for treating cancer...