US Patent Issued to Regeneron Pharmaceuticals on March 25 for "Nucleic acid molecules encoding bispecific anti-BCMA x anti-CD3 antibodies" (New York, Massachusetts Inventors)

ALEXANDRIA, Va., March 26 -- United States Patent no. 12,258,412, issued on March 25, was assigned to Regeneron Pharmaceuticals Inc. (Tarrytown, N.Y.).

"Nucleic acid molecules encoding bispecific anti-BCMA x anti-CD3 antibodies" was invented by Eric Smith (New York), Kara Olson (White Plains, N.Y.), Frank Delfino (Poughquag, N.Y.), David DiLillo (New York), Jessica Kirshner (New York), Olga Sineshchekova (Pleasantville, N.Y.) and Qian Zhang (Lexington, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "B-cell maturation antigen (BCMA) is expressed on malignant plasma cells. The present invention provides novel bispecific antibodies (bsAbs) that bind to both BCMA and CD3 and activate T cells via the CD3 com...