ALEXANDRIA, Va., June 19 -- United States Patent no. 12,331,341, issued on June 17, was assigned to Regeneron Pharmaceuticals Inc. (Tarrytown, N.Y.).
"Serum-free cell culture medium" was invented by Shadia Abike Oshodi (Jersey City, N.J.), Amy S. Johnson (Briarcliff Manor, N.Y.) and Shawn M. Lawrence (Nyack, N.Y.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The specification describes an improved serum-free animal cell culture medium, which can used for the production of a protein of interest. Ornithine, or a combination of ornithine and putrescine can be added to serum-free media or chemically defined media to improve viable cell density, to reduce cell doubling time, and to increase the production of a p...