ALEXANDRIA, Va., Jan. 29 -- United States Patent no. 12,207,628, issued on Jan. 28, was assigned to Regeneron Pharmaceuticals Inc. (Tarrytown, N.Y.).
"ADAM6 mice" was invented by Lynn Macdonald (Harrison, N.Y.), Sean Stevens (Del Mar, Calif.), Andrew J. Murphy (Croton-on-Hudson, N.Y.) and Margaret Karow (Santa Rosa Valley, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Mice are provided that comprise a reduction or deletion of ADAM6 activity from an endogenous ADAM6 locus, or that lack an endogenous locus encoding a mouse ADAM6 protein, wherein the mice comprise a sequence encoding an ADAM6 or ortholog or homolog or fragment thereof that is functional in a male mouse. In one embodiment, the sequence i...