ALEXANDRIA, Va., Jan. 28 -- United States Patent no. 12,535,490, issued on Jan. 27, was assigned to REGENERON PHARMACEUTICALS INC. (Tarrytown, N.Y.).

"Affinity chromatography-coupled native mass spectrometry for antibody analysis" was invented by Shunhai Wang (Scarsdale, N.Y.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides rapid, sensitive high-throughput methods and systems for characterizing peptides or proteins using affinity-based chromatography-coupled native mass spectrometry to improve manufacturing process of biopharmaceutical products, such as identifying impurities during antibody purification, monitoring post-translational modification variants during production, or c...