ALEXANDRIA, Va., Jan. 20 -- United States Patent no. 12,528,883, issued on Jan. 20, was assigned to Regeneron Pharmaceuticals Inc. (Tarrytown, N.Y.).

"Compositions and methods for making antibodies based on use of expression-enhancing loci" was invented by Robert Babb (River Edge, N.J.), Darya Burakov (Tarrytown, N.Y.), Gang Chen (Yorktown Heights, N.Y.), James P. Fandl (LaGrangeville, N.Y.) and Yu Zhao (Williston Park, N.Y.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This invention relates to site-specific integration and expression of recombinant proteins in eukaryotic cells. In particular, the invention includes compositions and methods for improved expression of antigen-binding proteins including mono...