US Patent Issued to Regeneron Pharmaceuticals on Feb. 3 for "Characterization of impurities in adeno-associated virus (AAV) samples and formulation compositions to stabilize AAV" (New York, California Inventors)

ALEXANDRIA, Va., Feb. 3 -- United States Patent no. 12,540,333, issued on Feb. 3, was assigned to Regeneron Pharmaceuticals Inc. (Tarrytown, N.Y.).

"Characterization of impurities in adeno-associated virus (AAV) samples and formulation compositions to stabilize AAV" was invented by Dingjiang Liu (Pleasantville, N.Y.), Bowen Jiang (Foster City, Calif.) and Franco Tzul (Cortlandt Manor, N.Y.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods for characterizing DNA impurities in adeno-associated virus (AAV) samples or biopharmaceuticals are provided including the use of size exclusion chromatography and spectrophotometry. Methods and compositions are also provided to minimize leakage of packed DNA from AAV ...