US Patent Issued to Regeneron Pharmaceuticals on Dec. 23 for "Compositions and methods for making antibodies based on use of an expression-enhancing locus" (New York, New Jersey Inventors)

ALEXANDRIA, Va., Dec. 23 -- United States Patent no. 12,503,520, issued on Dec. 23, was assigned to Regeneron Pharmaceuticals Inc. (Tarrytown, N.Y.).

"Compositions and methods for making antibodies based on use of an expression-enhancing locus" was invented by Robert Babb (River Edge, N.J.), Darya Burakov (Tarrytown, N.Y.), Gang Chen (Yorktown Heights, N.Y.) and James P. Fandl (LaGrangeville, N.Y.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This invention relates to site-specific integration and expression of recombinant proteins in eukaryotic cells. In particular, the invention includes compositions and methods for improved expression of antibodies including bispecific antibodies in eukaryotic cells, par...