US Patent Issued to Regeneron Pharmaceuticals on Dec. 2 for "Mice that make VL binding proteins" (New York, California Inventors)

ALEXANDRIA, Va., Dec. 2 -- United States Patent no. 12,486,335, issued on Dec. 2, was assigned to Regeneron Pharmaceuticals Inc. (Tarrytown, N.Y.).

"Mice that make VL binding proteins" was invented by Lynn Macdonald (Harrison, N.Y.), Sean Stevens (Del Mar, Calif.), Cagan Gurer (Chappaqua, N.Y.), Karolina A. Meagher (Yorktown Heights, N.Y.) and Andrew J. Murphy (Croton-on-Hudson, N.Y.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Genetically modified mice and methods for making an using them are provided, wherein the mice comprise a replacement of all or substantially all immunoglobulin heavy chain V gene segments, D gene segments, and J gene segments with at least one light chain V gene segment and at least...