ALEXANDRIA, Va., Aug. 26 -- United States Patent no. 12,398,176, issued on Aug. 26, was assigned to Regeneron Pharmaceuticals Inc. (Tarrytown, N.Y.).
"Use of Raman spectroscopy in downstream purification" was invented by Christina Passno (Tarrytown, N.Y.), Christopher Cowan (Tarrytown, N.Y.) and Andrew Tustian (Tarrytown, N.Y.).
According to the abstract* released by the U.S. Patent & Trademark Office: "In situ Raman spectroscopy methods and systems for characterizing or quantifying a protein purification intermediate and/or final concentrated pool during production or manufacture are provided. In one embodiment, in situ Raman spectroscopy is used to characterize or quantify protein purification intermediates critical quality attributes d...