ALEXANDRIA, Va., Oct. 8 -- United States Patent no. 12,435,356, issued on Oct. 7, was assigned to RedVault Biosciences LP (Houston).
"Target reporter constructs and uses thereof" was invented by Michael L. Metzker (Houston) and Christopher August Weier (Houston).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are methods and compositions for the detection of target nucleic acids using target reporter constructs (TRCs) which comprise target sequences complementary to the target nucleic acid. Further provided are methods of replicating the TRCs using rolling circle replication and/or rolling circle amplification to produce replicated TRCs which can be detected using probe sequences within the rep...