ALEXANDRIA, Va., Nov. 18 -- United States Patent no. 12,474,289, issued on Nov. 18, was assigned to Ravi Saraf (Lincoln, Neb.).
"Molecular binary probe to quantify nucleic acid sequences and mutations" was invented by Ravi Saraf (Lincoln, Neb.) and Rahul Tevatia (Germantown, Md.).
According to the abstract* released by the U.S. Patent & Trademark Office: "A binary probe composed of long and short nucleic acid (NA) or peptide nucleic acid (PNA) chains immobilized on an electrode to electrochemically detect specific sequences of single stranded nucleic acids extracted from biospecimens by specific binding to a single spot or and an array of spots of the probe molecules. The short chain is tethered to the electrode at one end and the other e...