ALEXANDRIA, Va., Dec. 9 -- United States Patent no. 12,492,373, issued on Dec. 9, was assigned to RACTHERA Co. LTD. (Tokyo) and RIKEN (Wako, Japan).
"Production method for nerve tissue" was invented by Atsushi Kuwahara (Kobe, Japan), Suguru Yamasaki (Kobe, Japan), Yasushi Hiramine (Kobe, Japan), Yoshiki Sasai (Wako, Japan) and Masayo Takahashi (Wako, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a method for producing neural cells or a neural tissue, including the following steps (1)-(3):(1) a first step of culturing pluripotent stem cells in the absence of feeder cells and in a medium containing 1) a TGFBeta family signal transduction pathway inhibiting substance and/or...