ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,454,517, issued on Oct. 28, was assigned to R.J. Reynolds Tobacco Co. (Winston-Salem, N.C.).

"Nicotine salts, co-crystals, and salt co-crystal complexes" was invented by Gary M. Dull (Lewisville, N.C.), Andrew Carr (Cambridge, Great Britain) and Emma Sharp (Cambridgeshire, Great Britain).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides certain nicotine salts, co-crystals, and salt co-crystals and provides novel polymorphic forms of certain nicotine salts. In particular, nicotine salts with mucic acid, 3,5-dihydroxybenzoic acid, and 2,3-dihydroxybenzoic acid, and crystalline polymorphic forms of nicotine 4-acetamidobenzoate, nicotine ...