US Patent Issued to Quest Diagnostics Investments on March 18 for "Mass spectrometric quantitation assay for metabolites of leflunomide" (California Inventor)

ALEXANDRIA, Va., March 19 -- United States Patent no. 12,253,532, issued on March 18, was assigned to Quest Diagnostics Investments LLC (Secaucus, N.J.).

"Mass spectrometric quantitation assay for metabolites of leflunomide" was invented by Karin O. Thomassian (Tujunga, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method for determining an amount of teriflunomide in a sample by mass spectrometry includes adding an internal standard to the sample, subjecting the sample to solid phase extraction, purifying the sample by high turbulence liquid chromatography, ionizing the sample to produce one or more teriflunomide ions detectable by mass spectrometry, determining the amount of the one or more terifl...