US Patent Issued to Queen's University at Kingston on March 4 for "Cytotoxic actin-targeting compounds" (Canadian Inventors)

ALEXANDRIA, Va., March 5 -- United States Patent no. 12,239,639, issued on March 4, was assigned to Queen's University at Kingston (Kingston, Canada).

"Cytotoxic actin-targeting compounds" was invented by Rebecca Grange (Kingston, Canada), John Allingham (Kingston, Canada), Andrew Craig (Kingston, Canada), P. Andrew Evans (Kingston, Canada) and Madhu Aeluri (Kingston, Canada).

According to the abstract* released by the U.S. Patent & Trademark Office: "A class of compounds useful in pharmaceutical compositions and methods for treating or preventing cancer is described. Analogs of Mycalolide B have been prepared and tested in breast and ovarian cancer cell lines. The compounds show utility for inhibition of survival and proliferation of tum...