ALEXANDRIA, Va., March 19 -- United States Patent no. 12,251,433, issued on March 18, was assigned to QUADRAM INSTITUTE BIOSCIENCE (Norwich, Great Britain) and UEA ENTERPRISES Ltd. (Norwich, Great Britain).
"Engineering gut commensal bacteria to express heterologous proteins in their outer membrane vesicles (OMVS) for delivery to the GI-tract" was invented by Regis Gabriel Stentz (Norwich, Great Britain) and Simon Richard Carding (Norwich, Great Britain).
According to the abstract* released by the U.S. Patent & Trademark Office: "This invention relates to the delivery of heterologous peptides or proteins such as therapeutic peptides, therapeutic proteins or antigens to mucosal sites using vesicles derived from the outer membrane of commen...