ALEXANDRIA, Va., Aug. 26 -- United States Patent no. 12,398,391, issued on Aug. 26, was assigned to QIAGEN Sciences LLC (Germantown, Md.).
"Semi-random barcodes for nucleic acid analysis" was invented by Yexun Wang (Ellicott City, Md.) and Zhong Wu (Poolesville, Md.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides oligonucleotides that comprise semi-random barcode sequences. Such oligonucleotides may be incorporated into reverse transcription primers, PCR primers, or portions of sequencing adapters in preparing sequencing libraries. The resulting sequencing libraries can be used for accurate sequencing, including DNA or RNA counting and mutation detection. Methods and kits for p...