ALEXANDRIA, Va., July 3 -- United States Patent no. 12,343,403, issued on July 1, was assigned to Purdue Research Foundation (West Lafayette, Ind.).
"Targeted ligand-payload based drug delivery for cell therapy" was invented by Philip S. Low (West Lafayette, Ind.), Madduri Srinivasarao (West Lafayette, Ind.) and Boning Zhang (West Lafayette, Ind.).
According to the abstract* released by the U.S. Patent & Trademark Office: "A drug delivery platform providing flexible fine tune of cell therapy is disclosed herein. Particularly, an engineered fusion protein is coupled with a high affinity ligand carrying at least one payload of drug to be internalized by the transplanted cell to observe or regulate transplanted cell therapy effects."
The pa...