US Patent Issued to Purdue Research Foundation, Genentech on Aug. 26 for "Rapid depressurization controlled ice nucleation in pharmaceutical freeze-drying" (Indiana, California Inventors)

ALEXANDRIA, Va., Aug. 26 -- United States Patent no. 12,398,953, issued on Aug. 26, was assigned to Purdue Research Foundation (West Lafayette, Ind.) and Genentech Inc. (South San Francisco, Calif.).

"Rapid depressurization controlled ice nucleation in pharmaceutical freeze-drying" was invented by Andrew Strongrich (West Lafayette, Ind.), Alina Alexeenko (West Lafayette, Ind.), Fredric John Lim (Fremont, Calif.) and Lokesh Kumar (San Mateo, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A lyophilization method for lyophilizing products inside one or more vials within a lyophilization chamber is disclosed which includes humidifying a charge gas to a predetermined relative humidity, cooling shelves in t...