US Patent Issued to PTC Therapeutics MP on March 25 for "Compositions and methods for increasing tetrahydrobiopterin plasma exposure" (North Carolina, Massachusetts Inventors)

ALEXANDRIA, Va., March 26 -- United States Patent no. 12,257,252, issued on March 25, was assigned to PTC Therapeutics MP Inc. (Warren, N.J.).

"Compositions and methods for increasing tetrahydrobiopterin plasma exposure" was invented by Neil Smith (Cary, N.C.) and Jonathan Reis (Brookline, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention features compositions including sepiapterin, or a pharmaceutically acceptable salt thereof, and methods for the treatment of BH4-related disorders. In some embodiments, these compositions and methods result in an increase in plasma exposure of BH4."

The patent was filed on May 30, 2019, under Application No. 17/059,632.

*For further information, i...