US Patent Issued to PROXYGEN on Sept. 9 for "Oxazole and thioazole-type cullin ring ubiquitin ligase compounds and uses thereof" (Austrian Inventors)

ALEXANDRIA, Va., Sept. 10 -- United States Patent no. 12,410,152, issued on Sept. 9, was assigned to PROXYGEN GMBH (Vienna).

"Oxazole and thioazole-type cullin ring ubiquitin ligase compounds and uses thereof" was invented by Georg Winter (Vienna), Cristina Mayor Ruiz (Vienna) and Stefan Kubicek (Vienna).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to compounds with the ability to stimulate/induce ubiquitination of a target protein/target proteins. The compounds of the present invention may stimulate/induce ubiquitination of a target protein/target proteins; i.e. via degradation of a target protein/target proteins by the cullin-RING ubiquitin ligase (CRL). Such target protein/t...