ALEXANDRIA, Va., April 9 -- United States Patent no. 12,270,794, issued on April 8, was assigned to PROXCYS HOLDING B.V. (Emmen, Netherlands).
"Direct capture using large bead chromatography media" was invented by Marcellus Johannes Hubertus Raedts (Emmen, Netherlands).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed is a continuous process in which a subset of a number of mutually identical columns, are connected in series. The process liquid, e.g. crude cell culture harvest, is supplied to the most upstream column of the subset. It flows successively through the in series connected columns and leaves the subset through the most downstream and flows into the downstream collection vessel. As soon as t...