ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,385,048, issued on Aug. 12, was assigned to Proteonic Biotechnology IP B.V. (Leiden, Netherlands).

"Construct and sequence for enhanced gene expression" was invented by Maurice Wilhelmus van der Heijden (Gouda, Netherlands) and Bart Marinus Engels (Woerden, Netherlands).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to a method for transcription and expression using a nucleic acid construct which is characterized by the presence of a promoter followed by an intronic promoter. The invention further relates to a nucleic acid construct, an expression vector and a cell comprising the construct, and its use. The invention also relates to...