US Patent Issued to Promega on Nov. 4 for "Luciferase sequences utilizing infrared-emitting substrates to produce enhanced luminescence" (Wisconsin Inventors)

ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,460,245, issued on Nov. 4, was assigned to Promega Corp. (Madison, Wis.).

"Luciferase sequences utilizing infrared-emitting substrates to produce enhanced luminescence" was invented by Lance P. Encell (Fitchburg, Wis.), Mary P. Hall (Waunakee, Wis.), Keith V. Wood (Madison, Wis.) and Monika G. Wood (Madison, Wis.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are isolated polynucleotide encoding modified click beetle luciferase polypeptides that have enhanced luminescence and longer wavelength near-infrared signals. The disclosure also relates to near-infrared bioluminescence systems that include said modified click beetle luciferase poly...