US Patent Issued to Promega on Feb. 10 for "Luciferase enzymes for use with thermostable luciferins in bioluminescent assays" (Wisconsin Inventors)

ALEXANDRIA, Va., Feb. 11 -- United States Patent no. 12,545,899, issued on Feb. 10, was assigned to Promega Corp. (Madison, Wis.).

"Luciferase enzymes for use with thermostable luciferins in bioluminescent assays" was invented by Michael Killoran (Madison, Wis.), Ce Shi (Madison, Wis.), Mary Hall (Madison, Wis.), Lance P. Encell (Madison, Wis.) and Thomas Kirkland (Madison, Wis.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are enhanced luciferase enzymes for use with thermostable luciferin analogs for bioluminescent assays. In particular, the present disclosure provides compositions, assays, and methods for performing a bioluminescent assay using enhanced, high-activity luciferase enzymes c...