ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,448,443, issued on Oct. 21, was assigned to ProMab Biotechnologies Inc. (Richmond, Calif.) and Forevertek Biotechnology Co. Ltd (Changsha, China).
"CS1 antibody and anti-CS1-CAR-t cells" was invented by Lijun Wu (Albany, Calif.) and Vita Golubovskaya (Richmond, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention is directed to a monoclonal anti-human CS1 antibody or a single-chain variable fragment (scFv), comprising VH having the amino acid of SEQ ID NO: 3 and VL having the amino acid of SEQ ID NO: 7. The present invention is also directed to a chimeric antigen receptor fusion protein comprising from N-terminus to C-terminus: (i...