ALEXANDRIA, Va., June 17 -- United States Patent no. 12,312,370, issued on May 27, was assigned to Principia Biopharma Inc. (Bridgewater, N.J.).
"Immunoproteasome inhibitors" was invented by Yan Lou (Pleasanton, Calif.), Timothy Duncan Owens (Redwood City, Calif.), Kenneth Albert Brameld (Hillsborough, Calif.) and David Michael Goldstein (Redwood City, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are compounds, such as a compound of Formula (I), or a pharmaceutically acceptable salt thereof, that are immunoproteasome (such as LMP2 and LMP7) inhibitors. The compounds described herein can be useful for the treatment of diseases treatable by inhibition of immunoproteasomes. Also provide...