US Patent Issued to President and Fellows of Harvard College on March 18 for "Compositions and methods for reducing tactile dysfunction, anxiety, and social impairment" (Massachusetts Inventors)

ALEXANDRIA, Va., March 19 -- United States Patent no. 12,252,457, issued on March 18, was assigned to President and Fellows of Harvard College (Cambridge, Mass.).

"Compositions and methods for reducing tactile dysfunction, anxiety, and social impairment" was invented by David D. Ginty (Boston), Lauren L. Orefice (Boston) and Jinbo Lee (Andover, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention features novel peripherally-restricted isoguvacine analogs with reduced blood brain barrier permeability and methods of use thereof for reducing tactile dysfunction, social impairment, and anxiety in a subject diagnosed with Autism Spectrum Disorder, Rett syndrome, Phelan McDermid syndrome, or ...