ALEXANDRIA, Va., June 19 -- United States Patent no. 12,331,347, issued on June 17, was assigned to President and Fellows of Harvard College (Cambridge, Mass.).

"Methods for high-throughput labelling and detection of biological features in situ using microscopy" was invented by George M. Church (Brookline, Mass.), Je-Hyuk Lee (Allston, Mass.) and Evan R. Daugharthy (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods of labelling one or more subcellular components (e.g., an organelle and/or subcellular region) in vivo are provided. Methods of labelling a protein in vivo are provided. Methods of determining a nucleic acid sequence in situ are also provided."

The patent was filed on Jan. 2...