US Patent Issued to President and Fellows of Harvard College, The Broad Institute on July 15 for "Methods and compositions for evolving base editors using phage-assisted continuous evolution (PACE)" (Massachusetts Inventors)

ALEXANDRIA, Va., July 16 -- United States Patent no. 12,359,218, issued on July 15, was assigned to President and Fellows of Harvard College (Cambridge, Mass.) and The Broad Institute Inc. (Cambridge, Mass.).

"Methods and compositions for evolving base editors using phage-assisted continuous evolution (PACE)" was invented by David R. Liu (Cambridge, Mass.), Benjamin Thuronyi (Cambridge, Mass.) and Christopher Gerard Wilson (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The instant specification provides for evolved base editors which overcome deficiencies of those in art (including increased efficiency and/or decreased requirement for specific sequence-context at an editing site) and which ...