US Patent Issued to President and Fellows of Harvard College, Eisai R&D Management on Sept. 23 for "Macrocyclic compound and uses thereof" (Japanese, American Inventors)

ALEXANDRIA, Va., Sept. 23 -- United States Patent no. 12,421,248, issued on Sept. 23, was assigned to President and Fellows of Harvard College (Cambridge, Mass.) and Eisai R&D Management Co. Ltd. (Tokyo).

"Macrocyclic compound and uses thereof" was invented by Yoshito Kishi (Cambridge, Mass.), Kazunobu Kira (Tsukuba, Japan) and Ken Ito (Tsukuba, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides novel Compound (1) having tumor vascular remodeling effect and/or anti-CAF (Cancer Associated Fibroblasts) activity, or a pharmaceutically acceptable salt thereof, optionally in a pharmaceutically acceptable carrier, and medical uses thereof."

The patent was filed on June 21, 2023, u...