US Patent Issued to Prelude Therapeutics on Oct. 21 for "BRM targeting compounds and associated methods of use" (Delaware, Pennsylvania Inventors)

ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,448,389, issued on Oct. 21, was assigned to Prelude Therapeutics Inc. (Wilmington, Del.).

"BRM targeting compounds and associated methods of use" was invented by Liang Lu (Hockessin, Del.), Andrew Paul Combs (Kennett Square, Pa.), Corey Howard Basch (Delmar, Del.), Rupa Shetty (Blue Bell, Pa.), Chaofeng Dai (Hockessin, Del.), Klare Lazor Bersch (Glen Mills, Pa.), John A. Rose (Wilmington, Del.), Danielle Julie Beam (Newark, Del.) and Song Mei (Wilmington, Del.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides bifunctional compounds comprising a target protein binding moiety and a E3 ubiquitin ligase binding moiety, and assoc...